Wales coach Warren Gatland has had the Springboks’ number for some years now.
Ahead of Saturday's meeting between the two sides at the Principality Stadium in Cardiff, Gatland has masterminded four wins over South Africa in his last five outings.
Wales’s latest win was in Rassie Erasmus’s first match in charge of the national team when the two teams clashed in the US in June.
The Dragons won that encounter 22-20 after a late charge-down try from the boot of Bok replacement flyhalf Robert du Preez.
South Africa, meanwhile, have not enjoyed a good record against the big teams in recent years.
Currently ranked fifth in the world, South Africa have beaten the world’s No.1 team New Zealand once in their last five outings; Ireland, in second, twice; and England, who are in fourth, two times.
Under Erasmus, though, that record looks a bit better as they beat the All Blacks once in their two outings in 2018, England twice in four matches and have avoided Ireland.
Against Wales, who are ranked third, it’s time for revenge and Erasmus has a chance to get his personal record against Gatland and his team up to 50 percent with a win on Saturday.
Erasmus knows it won’t be easy and said earlier in the week that he “rates Gatland as a coach” and that this will be their toughest match on the tour of Europe.
In search of a perfect November series, having beaten Scotland, Australia and Tonga to date, Gatland is confident of ending the year on a high.
The New Zealander says: “We have had some good success over South Africa in recent years, so it will be important for us to build on that.
“It would be nice to have a clean sweep…”