After securing the Reds’ place in a European semifinal with a stunning comeback win over former club Borussia Dortmund, Klopp made 10 changes to the side that beat Bournemouth 2-1 on Sunday.
And the German says he will make the decisions he feels will bring silverware to Anfield this season without prioritising competition.
He says: “We had no other chance to win [other than to make changes].
“I said to the boys maybe sometimes rotation is for resting players for another tournament.
“In our case, we only rotate because the most important tournament still and always will be the Premier League, and we want to win this game.
“You cannot rest for a tournament, you can only try to find a few more fit players, that’s what we tried to do.
“We have two more Prem games before the next European game.”