British and Irish Lions coach Warren Gatland has made six changes to the starting XV which lost to the Springboks last Saturday in Cape Town.
The tour’s leading try-scorer, Josh Adams makes his Lions Test debut on the right wing, joining Duhan van der Merwe who keeps his place on the left.
Liam Williams is added at fullback to complete the back three.
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Ireland’s Bundee Aki is included at inside centre to win his Lions first Test cap, joining Robbie Henshaw who switches to 13.
Dan Biggar is retained at flyhalf with Ali Price starting at scrumhalf, having been named as a replacement last weekend.
In the pack, there are two changes to the front-row with injury-free Wyn Jones taking his place at loosehead to make his Lions Test debut alongside Ken Owens, who is promoted from the bench to start his first Test of the tour at hooker.
Of his team, Gatland says: “The match-day 23 have an incredibly special opportunity in front of them – to seal a Lions series victory in South Africa.
“It doesn’t get much bigger than this and we’re excited by the challenge that faces us on Saturday.
“We’ve no excuses from last week. The Springboks put us under pressure in the second half and deserved the win. We have to be much better than that second half performance, and I believe we will be.”
British and Irish Lions: 15 Liam Williams, 14 Josh Adams, 13 Robbie Henshaw, 12 Bundee Aki, 11 Duhan van der Merwe, 10 Dan Biggar, 9 Ali Price, 8 Jack Conan, 7 Tom Curry, 6 Courtney Lawes, 5 Alun Wyn Jones (captain), 4 Maro Itoje, 3 Tadhg Furlong, Ken Owens and 1 Wyn Jones. Replacements: 16 Luke Cowan-Dickie, 17 Mako Vunipola, 18 Kyle Sinckler, 19 Adam Beard, 20 Sam Simmonds, 21 Conor Murray, 22 Finn Russell, 23 Elliot Daly.