Canleesha Meyers, 13, was last seen on Tuesday and was dressed in her school uniform which is a green jersey, pants and white T-shirt and green headband and shoes.
Ashtonay Visagie, 14, also disappeared while wearing a green jersey, pants and white T-shirt and green headband and shoes.
VANISH: Ashtonay, 14
It is believed the girls had been in the vicinity of AME Primary School in Eikendal when they went missing.
If you have seen these girls, please contact Warrant Officer Beck on 021 980 5633 or the Pink Ladies 072 214 7439.