Temba Bavuma will get a one-off chance to show what he can do in the ODI arena.
The Lions star was called up for the 50-over clash against Ireland later this month after averaging 66 in recent Test matches.
That form has earned the Langa-born batsman a maiden call-up alongside Dwaine Pretorius and Andile Phehlukwayo.
Selection convenor Linda Zondi says: “We want to see what he can do in the ODI format after the extremely successful run he has had in the Test squad where he has averaged 66 during the current calendar year.”
Bavuma was not a Top 20 run-getter in last year’s domestic One-Day Cup.
He boasts 1 380 runs from 59 innings with a strike rate of just over 80 in his List A career and will have to improve his average of 26.73 if he is to be effective down the order.
Allrounder Pretorius, meanwhile, is also only in line to play against Ireland while paceman Phehlukwayo has been named in both squads on the back of their performances for South Africa A.
Dale Steyn and David Miller come back into the squad at the expense of Morne Morkel and Rilee Rossouw.
Zondi adds: “Andile was our leading wicket-taker for South Africa A in the recently concluded quadrangular series in Australia and he has been knocking on the door for some time following his strong performances in last season’s One-Day Cup. Both he and Dwaine have shown excellent form recently and the same applies to David Miller…”